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Peripheral Neuropathy Treatments

Top 10 Herbs & Supplements for Nerve Pain

Herbs for nerve pain

The fight against nerve pain caused by peripheral neuropathy can take many forms. For many, prescription medications are one way to reduce the pain. While prescription medications do provide much needed relief from nerve pain, their effectiveness is only temporary. Rather than seek to remedy the underlying cause of the pain, they merely mask the pain and other symptoms.

Another approach that has been used by millions of nerve pain sufferers is natural herbs and supplements that can help ease pain and address underlying problems that may be contributing to their neuropathy. For many neuropathy sufferers, this approach has a broad appeal as it can provide effective relief without many of the adverse side effects of prescription medications and painkillers. It also provides more lasting relief for many.

With that in mind, we scoured through hundreds of herbs and supplements that claim to be effective for the treatment of neuropathy. We’ve narrowed the list down to the top 10 herbs and supplements for effectively treating neuropathy pain and other symptoms related to nerve damage.

#1 – Vitamin B12

vitamin b12

According to the Journal of Neurological Science, vitamin B12 may increase protein synthesis and help in the regeneration of nerves. In ultra-high doses, it is shown to produce nerve regeneration. In addition to helping in the regeneration of damaged nerves, vitamin B12 is essential for maintaining healthy nerves and protecting them from damage. B12 helps build and support the myelin sheath, a layer of protective tissue around the nerves. This protective coating helps protect sensitive nerve tissue from foreign threats. If the myelin sheath is damaged or weakened, you may begin to experience neuropathic pain as the nerves have difficulty properly sending and receiving electric signals.


  • Promotes nerve health
  • Helps repair, rebuild and maintain the myelin sheath – a protective coating around the nerves
  • Promotes regeneration of damaged nerves (when taken in high doses)


#2 – Feverfew Extract 

Feverfew has made a name for itself as a natural treatment for migraines – but its healing powers extend into the realm of nerve pain as well. Feverfew contains a compound known as parthenolide, which is the secret to the herb’s pain relieving properties. For many suffering from nerve pain, chronic inflammation is common. The parthenolide in feverfew helps reduce inflammation by blocking the release of inflammatory substances in the body.


  • Prevent or reduce migraines
  • Relieve nerve pain
  • Reduce inflammation


#3 – Passionflower

passionflowerMany with neuropathy experience an overactive nervous system. The nerves transmit electrical signals at the slightest movement or touch, triggering intense pain in the hands or feet. An overactive nervous system and the pain associated with it can often lead to feelings of anxiety. Passionflower helps to relieve this anxiety and calm your overactive nerves.

Passionflower achieves its calming effect on the nerves is by increasing the levels of GABA (gamma aminobutyric acid) in the brain. GABA can help slow activity levels of brain cells, resulting in a calming effect on the body and mind.


  • Calms overactive nervous system
  • Relieves pain from over stimulated nerves
  • Reduces anxiety
  • Promotes sleep


#4 – Alpha Lipoic Acid

Alpha lipoic acid is a powerful antioxidant with the ability to regenerate itself. It can also regenerate other antioxidants and even B vitamins – which are essential for nerve health. As an antioxidant, alpha lipoic acid neutralizes the threat of free radicals in the body. These harmful substances damage and destroy cells in the body – which can eventually lead to chronic illnesses.

According to the University of Maryland Medical Center, “Several studies suggest alpha-lipoic acid helps lower blood sugar levels. Its ability to kill free radicals may help people with diabetic peripheral neuropathy, who have pain, burning, itching, tingling, and numbness in arms and legs from nerve damage. Researchers believe Alpha-lipoic acid helps improve insulin sensitivity.”

Alpha lipoic acid may also help those suffering from autonomic neuropathy, a form of neuropathy that affects internal organs such as the bladder, heart, digestive system and more.


  • Helps ease nerve-related pain, burning, itching, tingling and numbness
  • Kills free radicals
  • Lowers blood sugar levels


MORE: Learn more about the symptoms of Autonomic Neuropathy


#5 – Magnesium

Magnesium is an important mineral for nerve health. For starters, it is involved in over 300 chemical reactions in the body and helps maintain normal nerve and muscle function – among other things. Research suggests that the majority of Americans aren’t getting enough magnesium through their diet. This lack of magnesium can lead to increased levels of inflammation, which can in turn lead to other health problems like diabetes.

For those suffering from nerve pain, magnesium helps calm both the nervous system and your muscles – helping to ease nerve related pain. It can also ease anxiety and promote better sleep – which can be hugely beneficial to those whose nerve pain makes sleep difficult.


  • Helps regulate and reduce inflammation
  • Calms overactive nervous system
  • Calms muscles
  • Eases nerve pain
  • Promotes better sleep


#6 – CoQ10 (CoEnzyme Q10)

Your body produces the antioxidant Coenzyme Q10 naturally – though production levels decline with age. CoQ10 is important for nerve health because it helps address mitochondrial dysfunction, a condition that hurts the nerves and can lead to nerve damage and nerve pain. Like alpha lipoic acid, this antioxidant helps neutralize the threat of harmful free radicals in the body. It also plays an important role in helping the body convert food into energy to help fuel the body.


  • Corrects mitochondrial dysfunction (which can cause nerve pain)
  • Kills free radicals
  • Boosts energy


MORE: 3 Best Antioxidants for Easing Nerve Pain


#7 – Skullcap Extract

Anyone suffering from nerve pain knows first hand the stress and anxiety it can cause. When the nervous system becomes overactive and the nerves become overly sensitive to touch, it can leave you feeling on edge. By increasing blood flow to the brain, skullcap helps ease anxiety and calms an overactive nervous system. It also reduces pain associated with inflammation, which is a common problem associated with nerve damage.


  • Reduces anxiety
  • Calms nervous system
  • Reduces pain associated with inflammation


MORE: Learn more about how skullcap calms the nerves and reduces pain


#8 – Oat Straw Extract

Oat straw extract – which comes from green oats – has been used for centuries as an herbal treatment for improving the health of the mind and overall well-being of individuals. As it relates to neuropathy, it has a lot to offer. For those suffering from irritated skin as a result of nerve damage, oat straw extract can help relieve itchy or irritated skin. For those dealing with inflammation and swelling, it helps reduce inflammatory markers and relieve pain associated with inflammation. Finally, it helps calm the nervous system and ease anxiety.


  • Relieves itchy or irritated skin
  • Reduces inflammation
  • Calms nervous system and reduces anxiety


MORE: Four Ways to Relieve Neuropathy with Oat Straw


#9 – Acetyl-l-carnitine

Acetyl-l-carnitine is an amino acid whose primary function is to assist the body in producing energy. It also shows promise in helping to reduce the symptoms of neuropathy. According to the Washington University Pain Center, “L-acetylcarnitine is a promising compound for the treatment of painful neuropathies for its dual mechanisms, which include a significant analgesic effect after chronic administration and the ability to promote peripheral nerve regeneration and to improve vibration perception.”


  • Treats painful neuropathy
  • Promotes regeneration of peripheral nerves
  • Boosts energy


MORE: 5 Natural Treatments for Neuropathy


#10 – Inositol

Inositol is a carbohydrate found in foods like fruit, beans, grains and nuts – but can also be produced in a laboratory. According to WebMD, inositol helps balance chemicals in the body and is likely effective for treating diabetic nerve pain (among other things).


  • Helps ease diabetic nerve pain


Whether you’ve suffered for years or your diagnosis is new – herbs and supplements may provide much needed relief for your symptoms without many of the adverse side effects of prescription medications. They can also help address underlying causes of your nerve pain – providing more long-term reprieve from the painful symptoms of neuropathy. What herbs or supplements have been most effective for you in your battle with nerve pain?




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Did You Know?

20 million Americans suffer from peripheral neuropathy!

30% of cases, the cause is diabetes!
60-70% of diabetics have some nervous system damage in the U.S.
The annual medical expenses for diabetic neuropathy symptoms in the U.S. are as high as $13.7 billion annually.  (this does not include the other 70% of non diabetic cases!)


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Statements made here about The ReBuilder, Nerve Renew, magnet therapy, ozone, and peripheral neuropathy treatments have not been reviewed by the FDA. Statements about neuropathy and others topics are for information only and should not be used as a substitute for the advice of a physician or other licensed health care practitioner.  The ReBuilder has been proven 95% effective in clinical studies in reducing and even reversing the symptoms of peripheral neuropathy